Angela B. Lange was elected as a NASCE fellow in 2022. She is a Professor (Emeritus) of Biology, University of Toronto. She obtained her B.Sc. and Ph.D. from York University, Toronto, Canada, and in 1988 was awarded an NSERC University Research Fellowship bridging to a tenure-stream faculty position in the Department of Biology, University of Toronto Mississauga. Professor Lange was promoted to full professor in 1996. She received a variety of awards at UTM including the Research Excellence and Teaching Excellence Awards.
At the University of Toronto, Professor Lange has held a variety of key administrative positions, including Chair of the Department of Biology, Vice-Dean, Undergraduate, Teaching and Learning, Vice-Dean, Faculty and Acting Vice-Principal Academic & Dean, UTM.
Professor Lange is an internationally renowned scholar in the field of comparative insect endocrinology and physiology. She has examined hormonal, synaptic and neuromodulatory mechanisms that regulate reproductive, metabolic and cardiac physiology in insect model organisms. Professor Lange was one of the pioneering researchers in understanding the role of octopamine and adipokinetic hormones as metabolic hormones in the regulation of lipid mobilization during locust flight. In addition, she has identified, localized and characterized a variety of insect hormones and their receptors, which have mammalian orthologs; these include insulin-like peptides (insulin orthologs), adipokinetic hormone (GnRH), allatostatin-A (galanin), crustacean cardioactive peptide (neuropeptide S), SIFamide (GnIH), sulfakinin (cholecystokinin) and tachykinin-like peptides (substance P), amongst others. She has also worked extensively on the serotonergic and octopaminergic / tyraminergic (related to mammalian noradrenaline) signaling systems in various insects. As such, her pioneering comparative research has improved our understanding of the mechanisms by which these neurohormones and neuromodulators regulate diverse physiology and behavior in insects, and have facilitated our understanding of their vertebrate counterparts.
She has published over 180 scientific articles and 34 invited reviews and chapters in prestigious journals including PNAS, Annual Review of Entomology, Gen. Comp. Endocrinol, and J. Comp. Neurology. She has over 6680 citations, an h-index of 42 and i10-index of 161. She has presented 250 papers at scientific meetings and symposia with 38 invited papers. In 2021, Professor Lange received the Gorbman-Bern Memorial Lectureship for her significant work in comparative endocrinology. Professor Lange has trained over 200 highly qualified personnel many of whom have gone onto professional activities as faculty members, medical professionals, pharmaceutical and biotech industry members and educators.
Professor Lange was a member of the Natural Sciences and Engineering Research Council of Canada Grant Selection Committee for Biological Systems and Functions and a member of the selection committee for the NSERC Herzberg Canada Gold Medal Selection Committee, the Council’s highest research honor. She is currently an associate editor for Frontiers in Invertebrate Physiology. She has been a member of the International Federation of Comparative Endocrine Societies Council since 2005, and is currently interim Vice-President of the Council. She has been a member of NASCE since its inception in 2011 and has just stepped down as Secretary.
Lange personal website: https://www.utm.utoronto.ca/lange-lab/